Yibin Deng

Work focus: • Development of a skin model for the evaluation and validation of intradermal powder injection devices • Determination of the distribution and depths of the delivered fluorescently labeled particles in the model skin, human skin and pig skin using CLSM • Development of silica and PLGA nanoparticles as delivery systems of antigens and/or adjuvants • Encapsulation of the antigen-loaded nanoparticles into sugar-based microparticles that are suitable for powder injection

Work focus: • Investigation of conformational transition of silk fibroin proteins • A novel role of Mn(II) affecting the conformational transition process in silk fibroin was found using EPR and NMR Spectroscopy • Expression and purification of recombinant amyloid-β peptide (Aβ) • Analysis of the Aβ42 and investigation of its aggregation behavior under some effectors such as metal ions and some anti-oxidant compounds • Supervision of bachelor students for one semester in the experiments of analytica